MedILS
Search
Izbornik
Menu
Research
Miroslav Radman - Founder & scientific director
Groups
Biology of robustness
Skin eco-biology and biochemistry / NAOS-ILS lab
Cancer Signalling & Therapeutics
Publications
Scientists
IMPACT OBSERVATORY
Biophysics PhD programme
Icast
STIM
Alumni
Macromolecular homeostasis in aging
Intercellular Communication in Aging and Disease
Proteomics Research Group
Preventive and Regenerative Medicine
Laboratory for Translational research
ArtScience
Events
Event organization
Events calendar
Science popularization
Advances in Biomedical Research
City Split
Impressions
About us
About MedILS
Organization
Documents
Annual reports
Mission & vision
Contact
News
eng
hrv
Euraxess
HRS4R
Projects
Support
Jobs
Gallery
Web services
Cloud
FileSsender
Webmail
Links
Scientists
Scientist details
Back to list
Name: Igor Štagljar
E-mail:
igor.stagljar@medils.hr
Biography:
Curriculum vitae
LinkedIn:
LinkedIn profile page
Work group:
Cancer Signalling & Therapeutics
Publications at MedILS
CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system doi.org/10.15252/msb.202110629
D154Q Mutation does not Alter KRAS Dimerization PMID: 34896362 DOI: 10.1016/j.jmb.2021.167392
Mapping the Phospho-dependent ALK Interactome to Identify Novel Components in ALK Signaling doi.org/10.1016/j.jmb.2021.167283
Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells doi.org/10.1016/j.jmb.2021.167294
Drugging the undruggable proteins in cancer: A systems biology approach. doi.org/10.1016/j.cbpa.2021.07.004
Receptor tyrosine kinases and cancer: oncogenic mechanisms and therapeutic approaches doi.org/10.1038/s41388-021-01841-2
Toward the discovery of biological functions associated with the mechanosensor Mtl1p of Saccharomyces cerevisiae via integrative multi-OMICs analysis
A homogeneous split-luciferase assay for rapid and sensitive detection of anti-SARS CoV-2 antibodies ,https://doi.org/10.1038/s41467-021-22102-6 O
Protein Interactions of the Mechanosensory Proteins Wsc2 and Wsc3 for Stress Resistance in Saccharomyces cerevisiae, G3 (Bethesda). 2020 Jul 8: g3.401468.2020. DOI: 10.1534/g3.120.401468 PMID: 32641451
REEP5 depletion causes sarco(endo)plasmic reticulum vacuolization and cardiac functional defects, Nature Communication 11 (1) 569, PMID 32075961.
Split Intein Mediated Protein Ligation (SIMPL), a method for detecting protein-protein interactions and their inhibition, Nature Communications 2020 May 15;11(1): 2440. doi: 10.1038/s41467-020-16299-1 PMID: 32415080
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D. Nat Commun. 2020 Jan 24;11(1):499. doi: 10.1038/s41467-019-14224-9. PMID: 31980649; PMCID: PMC6981206.
A drug discovery platform to identify compounds that inhibit EGFR triple mutants
Highly Combinatorial Genetic Interaction Analysis Reveals a Multi-Drug Transporter Influence Network
Saraon P, Grozavu I, Stagljar I. Testing cancer inhibitors at scale. Nat Biomed Eng. 2018 Apr;2(4):203-204. doi: 10.1038/s41551-018-0226-x. PubMed PMID: 30936440.
Identification and Functional Testing of Novel Interacting Protein Partners for the Stress Sensors Wsc1p and Mid2p of Saccharomyces cerevisiae. G3 (Bethesda). 2019 Feb 7. pii: g3.200985.2018. doi: 10.1534/g3.118.200985. [Epub ahead of print] PubMed PMID: 30733383
Miroslav Radman - Founder & scientific director
Groups
Biology of robustness
Skin eco-biology and biochemistry / NAOS-ILS lab
Identification of aging targets
Identification of new molecules and others approaches
Rejuvenation molecules screening
Cancer Signalling & Therapeutics
Publications
Scientists
IMPACT OBSERVATORY
Biophysics PhD programme
Icast
STIM
Alumni
Probing protein carbonylation
Macromolecular homeostasis in aging
What is the role of protein stability and chaperones in longevity
What is the involvement of the mRNA quality control in cellular fitness and aging
How do some proteins avoid oxidation? Is protein oxidation a cooperative process where initial oxidation events would facilitate further deterioration?
Ubiquitin and cancer
Inflammation and cancer
Computational biophysics of macromolecules
Biophysics and bioinformatics
Mechanisms of neurodegeneration
Genetics of Death in Yeast
Intercellular Communication in Aging and Disease
Proteomics Research Group
Preventive and Regenerative Medicine
Sleep apnea
Cellular rejuvenation and clinical impact (CCL)
New paths for next-generation anti-aging approaches
Laboratory for Translational research